Fibrin-based Bioinks: New Tricks from an Old Dog

Anastasia Shpichka, Daria Osipova, Yuri Efremov, Polina Bikmulina, Nastasia Kosheleva, Marina Lipina, Evgeny A. Bezrukov, Roman B. Sukhanov, Anna B. Solovieva, Massoud Vosough, Peter Timashev

Article ID: 269
Vol 6, Issue 3, 2020, Article identifier:269

VIEWS - 1301 (Abstract) 224 (PDF)


For the past 10 years, the main efforts of most bioprinting research teams have focused on creating new bioink formulations, rather than inventing new printing set-up concepts. New tissue-specific bioinks with good printability, shape fidelity, and biocompatibility are based on “old” (well-known) biomaterials, particularly fibrin. While the interest in fibrin-based bioinks is constantly growing, it is essential to provide a framework of material’s properties and trends. This review aims to describe the fibrin properties and application in three-dimensional bioprinting and provide a view on further development of fibrin-based bioinks.


Fibrin, Bioink, Tissue engineering, Regenerative medicine, Bioprinting, Biofabrication

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