Application of Bioprinting in Ophthalmology

Authors

  • Yanfang Wang Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, Chongqing, 400045, China;Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangdong Provincial Key Laboratory of Medical Biomechanics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China;Guangdong Innovation Platform for Translation of 3D Printing Application, The third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
  • Jiejie Wang Department of Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China
  • Ziyu Ji College of Integrated Chinese and Western Medicine, Southwest Medical University, Lu Zhou 646000, China
  • Wei Yan Department of Anatomy, Hebei Medical University, Shijiazhuang 050011, China
  • Hong Zhao School of Basic Medicine, Guangdong Medical University, Dongguan, Guangdong 523000, China
  • Wenhua Huang Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangdong Provincial Key Laboratory of Medical Biomechanics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China;Guangdong Innovation Platform for Translation of 3D Printing Application, The third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China;Department of Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China
  • Huan Liu National Traditional Chinese Medicine Clinical Research Base, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China

DOI:

https://doi.org/10.18063/ijb.v8i2.552

Keywords:

Bioprinting, Ophthalmology, Bioinks, Biomaterials, Ocular bioprinting

Abstract

Three-dimensional (3D) bioprinting is an emerging technology that is widely used in regenerative medicine. With the continuous development of the technology, it has attracted great attention and demonstrated promising prospects in ophthalmologic applications. In this paper, we review the three main types of 3D bioprinting technologies: Vat polymerizationbased bioprinting, extrusion-based bioprinting, and jetting-based bioprinting. We also present in this review the analysis of the usage of both natural and synthesized hydrogels as well as the types of cells adopted for bioinks. Cornea and retina are the two main types of ocular tissues developed in bioprinting, while other device and implants were also developed for the ocular disease treatment. We also summarize the advantages and limitations as well as the future prospects of the current bioprinting technologies based on systematic reviews.

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2022-02-22

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Vol. 8 No. 2 (2022): International Journal of Bioprinting

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Review

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